UMODL1

Across TCGA patient cohorts, UMODL1 mutation is significantly associated with the RNA expression of many other genes, with 4,721 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UMODL1-associated genes across cancer lineages are ZMYND19, NUSAP1, and RNU6-321P. Each is linked with UMODL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both UMODL1-to-partner and partner-to-UMODL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZMYND19 grouped by UMODL1-low versus UMODL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UMODL1→partner) and Y-score (partner→UMODL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZMYND19 →	+0.447	+1.880	<.001	<.001	3	4
UCEC	NUSAP1 →	+0.547	+1.669	.001	<.001	3	4
HNSC	RNU6-321P →	+0.166	+4.441	<.001	.005	3	3
LUAD	RNA5SP45 →	+0.181	+5.757	<.001	<.001	3	3
LIHC	RNU6-7 →	+0.443	+3.397	<.001	.003	3	3
LIHC	MIR1268A →	+0.614	+3.448	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,721 associations by consensus.

ZMYND19 by UMODL1 expression — UCEC

Explore this box plot interactively →