Q-omics provides the consensus-scored RNU6-321P profile across patient tissues and cancer cell-line models. RNU6-321P expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in DLBC. Additionally, RNU6-321P RNA expression shows 8,724 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight DLBC, and COAD as cancer lineages where RNU6-321P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU6-321P survival associations across molecular data types. RNU6-321P RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-321P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	7	DLBC (54)	view →

This table ranks reproducible RNU6-321P RNA expression–survival associations across cancer types. High RNU6-321P expression shows unfavorable associations in DLBC, ESCA, PCPG, SKCM and STAD, but favorable associations in BLCA. The DLBC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .016). Together, the overview and detailed table identify DLBC as the clearest survival context for RNU6-321P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	II,III,IV	0.175	0.843	.016	54	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
BLCA	OS	Tertile	II,III,IV	1.000	0.415	.046	21	view →
PCPG	DFS	Tertile	All	0.070	0.936	<.001	18	view →
SKCM	DFS	Tertile	III,IV	0.290	0.678	.001	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →

Pink = unfavorable, green = favorable. all 7 lineages →

RNU6-321P-DLBC (OS)

Kaplan–Meier survival curve for RNU6-321P RNA expression in DLBC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU6-321P in patient tissues and cancer cell lines. In patient samples, RNU6-321P shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	8,724	COAD (2698)	view →
Function (RNA)	6,237	STAD (5696)	view →