UBE2V2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UBE2V2 mutation is significantly associated with the RNA expression of many other genes, with 2,665 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2V2-associated genes across cancer lineages are OR7E18P, RN7SKP112, and LINC01870. Each is linked with UBE2V2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2V2-to-partner and partner-to-UBE2V2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E18P grouped by UBE2V2-low versus UBE2V2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2V2→partner) and Y-score (partner→UBE2V2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCOR7E18P →+0.068+6.342<.001.00131
CESCRN7SKP112 →+0.141+5.669<.001.00331
CESCLINC01870 →+0.125+7.164<.001<.00131
CESCLINC00368 →+0.051+5.306<.001.00631
CESCCDK2AP2P3 →+0.121+5.201.001.00731
CESCRPL17P12 →+0.066+6.144<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,665 associations by consensus.

OR7E18P by UBE2V2 expression — CESC

Box plot of OR7E18P in UBE2V2-low vs UBE2V2-high samples in CESC.

Explore this box plot interactively →

Exploration