UBASH3B

Across TCGA patient cohorts, UBASH3B protein abundance is significantly associated with the RNA expression of many other genes, with 17,339 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible UBASH3B-associated genes across cancer lineages are RAC2, PELATON, and COTL1. Each is linked with UBASH3B in more than 7 cancer types. Because this analysis shows association rather than direction, both UBASH3B-to-partner and partner-to-UBASH3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBASH3B versus RAC2 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBASH3B→partner) and Y-score (partner→UBASH3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAC2 →	+1.002	+0.529	<.001	<.001	3	8
LSCC	PELATON →	+0.799	+0.325	<.001	<.001	3	8
BRCA	COTL1 →	+1.005	+0.523	<.001	<.001	3	7
CCRCC	ITGAX →	+0.765	+0.418	<.001	<.001	3	7
LSCC	PIK3R5 →	+0.851	+0.360	<.001	.002	3	7
GBM	DOK3 →	+0.728	+0.331	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,339 associations by consensus.

UBASH3B vs RAC2 — BRCA

Explore this scatter interactively →