TYRP1

Across TCGA cell cohorts, TYRP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,221 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TYRP1-associated GO terms across cancer lineages are Kidney development, Actin filament depolymerization, and Regulation of protein neddylation. Each is linked with TYRP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TYRP1-to-partner and partner-to-TYRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Kidney development grouped by TYRP1-low versus TYRP1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TYRP1→partner) and Y-score (partner→TYRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Kidney development →	-0.029	-2.851	.007	.005	3	7
CNS	Actin filament depolymerization →	+0.132	+1.098	<.001	.005	3	6
BREAST	Regulation of protein neddylation →	+0.090	+0.783	<.001	.007	3	6
SKIN	Ureteric bud morphogenesis →	-0.066	-3.754	.005	.004	3	6
PANCREAS	Positive regulation of monoatomic ion transmembrane transport →	-0.112	-0.199	<.001	<.001	3	5
PANCREAS	Response to potassium ion →	-0.157	-0.294	<.001	.002	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,221 associations by consensus.

Kidney development by TYRP1 expression — SKIN

Explore this box plot interactively →