TXNDC12

Across TCGA patient cohorts, TXNDC12 protein abundance is significantly associated with the RNA expression of many other genes, with 11,419 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TXNDC12-associated genes across cancer lineages are ABCG2, CIPC, and GNL2. Each is linked with TXNDC12 in more than 4 cancer types. Because this analysis shows association rather than direction, both TXNDC12-to-partner and partner-to-TXNDC12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TXNDC12 versus ABCG2 in CCRCC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC12→partner) and Y-score (partner→TXNDC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ABCG2 →	-1.377	-0.223	<.001	<.001	3	5
BRCA	CIPC →	-0.543	-0.233	<.001	<.001	3	5
UCEC	GNL2 →	+0.474	+0.240	.005	.001	3	4
BRCA	KIF2C →	+1.166	+0.412	<.001	<.001	3	4
BRCA	COA7 →	+0.587	+0.376	<.001	<.001	3	4
CCRCC	CGRRF1 →	-0.414	-0.216	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,419 associations by consensus.

TXNDC12 vs ABCG2 — CCRCC

Explore this scatter interactively →