TVP23A

Across TCGA patient cohorts, TVP23A mutation is significantly associated with the RNA expression of many other genes, with 1,277 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TVP23A-associated genes across cancer lineages are GSTA6P, PCNPP4, and RNU6-39P. Each is linked with TVP23A in more than 1 cancer types. Because this analysis shows association rather than direction, both TVP23A-to-partner and partner-to-TVP23A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSTA6P grouped by TVP23A-low versus TVP23A-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TVP23A→partner) and Y-score (partner→TVP23A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	GSTA6P →	+0.133	+5.010	<.001	.009	3	2
UCEC	PCNPP4 →	+0.147	+1.971	<.001	.009	3	2
SKCM	RNU6-39P →	+0.269	+3.508	<.001	.006	3	2
UCEC	RNU6-917P →	+0.252	+1.971	.001	.009	3	2
SKCM	LINC01217 →	+0.037	+4.147	<.001	.008	3	2
CESC	MIRLET7A2 →	+0.585	+6.342	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,277 associations by consensus.

GSTA6P by TVP23A expression — CESC

Explore this box plot interactively →