Q-omics provides the consensus-scored PCNPP4 profile across patient tissues and cancer cell-line models. PCNPP4 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in LUSC. Additionally, PCNPP4 RNA expression shows 12,236 significant protein co-abundance associations, with the highest sampling consensus in LUAD. Together, these results highlight LUSC, and LUAD as cancer lineages where PCNPP4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes PCNPP4 survival associations across molecular data types. PCNPP4 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

PCNPP4 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	10	LUSC (69)	view →

This table ranks reproducible PCNPP4 RNA expression–survival associations across cancer types. High PCNPP4 expression shows unfavorable associations in LUSC, KIRC, STAD, PAAD, THYM and GBM. The LUSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LUSC as the clearest survival context for PCNPP4 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	III,IV	0.197	0.603	<.001	69	view →
KIRC	DFS	Tertile	All	0.224	0.648	<.001	24	view →
STAD	OS	Tertile	IV	0.138	0.585	.010	18	view →
PAAD	DFS	Tertile	II,III,IV	0.101	0.474	<.001	18	view →
THYM	DFS	Tertile	II,III,IV	0.621	0.933	.009	18	view →
GBM	OS	Tertile	All	0.319	0.438	.028	15	view →

Pink = unfavorable, green = favorable. all 10 lineages →

PCNPP4-LUSC (OS)

Kaplan–Meier survival curve for PCNPP4 RNA expression in LUSC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with PCNPP4 in patient tissues and cancer cell lines. In patient samples, PCNPP4 shows the broadest associations at the RNA and protein expression levels, with LUAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	12,236	LUAD (5336)	view →
Function (RNA)	5,578	STAD (4967)	view →