PCNPP4

Across TCGA patient cohorts, PCNPP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,578 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PCNPP4-associated GO terms across cancer lineages are Positive regulation of DNA repair, Vesicle localization, and Cellular respiration. Each is linked with PCNPP4 in more than 10 cancer types. Because this analysis shows association rather than direction, both PCNPP4-to-partner and partner-to-PCNPP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by PCNPP4-low versus PCNPP4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNPP4→partner) and Y-score (partner→PCNPP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA repair →	+0.063	+0.055	<.001	<.001	3	11
STAD	Vesicle localization →	+0.061	+0.056	<.001	<.001	3	10
COAD	Cellular respiration →	+0.095	+0.048	<.001	<.001	3	9
STAD	Positive regulation of DNA metabolic process →	+0.066	+0.073	<.001	<.001	3	9
STAD	Regulation of transcription elongation by RNA polymerase II →	+0.076	+0.049	<.001	<.001	3	9
COAD	Aerobic respiration →	+0.100	+0.094	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,578 associations by consensus.

Positive regulation of DNA repair by PCNPP4 expression — STAD

Explore this box plot interactively →