PCNPP4

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PCNPP4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,236 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PCNPP4-associated proteins across cancer lineages are HMGN5, AGO1, and PURA. Each is linked with PCNPP4 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCNPP4-to-partner and partner-to-PCNPP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCNPP4 versus HMGN5 in LUAD, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNPP4→partner) and Y-score (partner→PCNPP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADHMGN5 →+0.581+0.552<.001.00135
UCECAGO1 →+0.237+0.750.005.00135
UCECPURA →+0.378+0.995<.001.00134
UCECUTRN_S1866 →+0.954+0.752<.001<.00134
LUADZBTB20 →+0.382+0.764<.001<.00134
LSCCZBTB20_S353 →+0.614+0.395.005.00934
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,236 associations by consensus.

PCNPP4 vs HMGN5 — LUAD

Per-sample scatter of PCNPP4 vs HMGN5 in LUAD (Pearson r = 0.36).

Explore this scatter interactively →

Exploration