TULP1

Across TCGA patient cohorts, TULP1 mutation is significantly associated with the RNA expression of many other genes, with 1,251 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TULP1-associated genes across cancer lineages are CIRBP-AS1, RPL23AP82, and PTP4A3. Each is linked with TULP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TULP1-to-partner and partner-to-TULP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CIRBP-AS1 grouped by TULP1-low versus TULP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TULP1→partner) and Y-score (partner→TULP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CIRBP-AS1 →	+0.546	+2.534	<.001	<.001	3	2
UCEC	RPL23AP82 →	+0.361	+2.095	<.001	.003	3	2
UCEC	PTP4A3 →	-0.792	-3.689	<.001	.001	3	2
UCEC	CIDECP1 →	+0.251	+3.186	.004	<.001	3	2
UCEC	COL27A1 →	-0.757	-2.668	<.001	<.001	3	2
UCEC	SRIP3 →	+0.331	+1.872	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,251 associations by consensus.

CIRBP-AS1 by TULP1 expression — UCEC

Explore this box plot interactively →