TULP1

Across TCGA pan-cancer cohorts, TULP1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated TULP1 data layer compared with 9 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TULP1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TULP1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

HNSC, KIRP, and KIRC are the cancer types where TULP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	0.730	0.558	<.001	103	view →
KIRP	OS	Quartile	All	0.531	0.855	<.001	93	view →
KIRC	DFS	Median	All	0.553	0.677	<.001	92	view →
SKCM	OS	Quartile	All	0.702	0.832	<.001	83	view →
UCS	DFS	Quartile	II,III,IV	0.706	0.121	.001	80	view →
UCEC	DFS	Median	All	0.554	0.731	<.001	76	view →
LIHC	DFS	Quartile	II,III,IV	0.272	0.450	.001	60	view →
LGG	DFS	Median	All	0.642	0.810	<.001	46	view →
UVM	OS	Median	III,IV	0.240	0.836	.001	30	view →
THYM	DFS	Tertile	II,III,IV	0.963	0.507	.001	29	view →
THCA	OS	Median	IV	0.570	0.939	.005	26	view →
ESCA	OS	Median	IV	0.698	0.222	.006	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

TULP1–HNSC (DFS)

Open the HNSC breakdown →