TULP1

Across TCGA pan-cancer cohorts, TULP1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of TULP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TULP1 RNA is repressed in tumor relative to normal tissue. In most cancer types TULP1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, LUSC, and KICH are the cancer types where TULP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TULP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.072	<.001	11	view →
LUSC	Male	All	+0.491	<.001	7	view →
KICH	All	All	−0.235	<.001	7	view →
LUAD	All	All	+0.136	<.001	6	view →
BRCA	Female	All	−0.130	.002	6	view →
PRAD	All	All	−0.462	<.001	2	view →
CHOL	All	All	+0.212	.003	2	view →
HNSC	Female	III,IV	−0.185	.014	2	view →
COAD	Female	All	+0.088	.037	1	view →
LIHC	All	II,III,IV	+0.013	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

TULP1–KIRC

Open the KIRC breakdown →