TULP1

Across TCGA cell cohorts, TULP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,613 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TULP1-associated GO terms across cancer lineages are Regulation of mRNA splicing, via spliceosome, Negative regulation of DNA-templated transcription initiation, and Negative regulation of RNA splicing. Each is linked with TULP1 in more than 8 cancer types. Because this analysis shows association rather than direction, both TULP1-to-partner and partner-to-TULP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA splicing, via spliceosome grouped by TULP1-low versus TULP1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TULP1→partner) and Y-score (partner→TULP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.069	+0.249	.001	.003	3	9
URINARY_TRACT	Negative regulation of DNA-templated transcription initiation →	+0.093	+0.167	<.001	<.001	3	8
URINARY_TRACT	Negative regulation of RNA splicing →	+0.100	+0.257	<.001	.003	3	8
BREAST	Flagellated sperm motility →	-0.086	-0.367	.001	.001	3	8
OESOPHAGUS	Negative regulation of transcription elongation by RNA polymerase II →	+0.136	+0.383	.002	.001	3	8
BREAST	Sperm motility →	-0.086	-0.367	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,613 associations by consensus.

Regulation of mRNA splicing, via spliceosome by TULP1 expression — URINARY_TRACT

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