TUBG2

Across TCGA patient cohorts, TUBG2 mutation is significantly associated with the RNA expression of many other genes, with 1,186 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBG2-associated genes across cancer lineages are RN7SL134P, RNY4P27, and PPME1. Each is linked with TUBG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBG2-to-partner and partner-to-TUBG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by TUBG2-low versus TUBG2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBG2→partner) and Y-score (partner→TUBG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.110	+2.484	.002	.001	3	2
BLCA	RNY4P27 →	+0.238	+4.229	<.001	.006	3	2
UCEC	PPME1 →	+0.444	+2.425	<.001	.002	3	2
UCEC	FTH1P15 →	+0.797	+3.343	.005	.005	3	2
UCEC	RNA5SP419 →	+0.644	+2.299	<.001	.001	3	2
UCEC	NAMPTP3 →	+0.251	+1.916	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,186 associations by consensus.

RN7SL134P by TUBG2 expression — UCEC

Explore this box plot interactively →