Q-omics provides the consensus-scored RNY4P27 profile across patient tissues and cancer cell-line models. RNY4P27 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in HNSC. Additionally, RNY4P27 RNA expression shows 5,668 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight HNSC, and STAD as cancer lineages where RNY4P27 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNY4P27 survival associations across molecular data types. RNY4P27 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNY4P27 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	HNSC (135)	view →

This table ranks reproducible RNY4P27 RNA expression–survival associations across cancer types. High RNY4P27 expression shows unfavorable associations in LIHC, LUSC, BLCA, PCPG and ESCA, but favorable associations in HNSC. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .011). Together, the overview and detailed table identify HNSC as the clearest survival context for RNY4P27 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	1.000	0.688	.011	135	view →
LIHC	OS	Tertile	All	0.144	0.688	.013	27	view →
LUSC	OS	Tertile	All	0.005	0.762	<.001	18	view →
BLCA	DFS	Tertile	III,IV	0.248	0.551	.031	18	view →
PCPG	DFS	Tertile	All	0.161	0.819	.004	18	view →
ESCA	OS	Tertile	II,III,IV	0.431	0.705	.013	9	view →

Pink = unfavorable, green = favorable. all 9 lineages →

RNY4P27-HNSC (DFS)

Kaplan–Meier survival curve for RNY4P27 RNA expression in HNSC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNY4P27 in patient tissues and cancer cell lines. In patient samples, RNY4P27 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,668	STAD (5405)	view →
RNA	3,051	LUSC (927)	view →