TUBG2

Across TCGA cell cohorts, TUBG2 mutation is significantly associated with the mutation status of many other genes, with 920 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TUBG2-associated genes across cancer lineages are DOCK9, CDHR5, and LBX1. Each is linked with TUBG2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TUBG2-to-partner and partner-to-TUBG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DOCK9 grouped by TUBG2-low versus TUBG2-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBG2→partner) and Y-score (partner→TUBG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	DOCK9 →	+4.297	+4.857	.009	.009	1	3
BREAST	CDHR5 →	+5.297	+5.297	.004	.004	1	3
LUNG_NSCLC_LUAD	LBX1 →	+4.772	+5.339	.004	.004	1	3
STOMACH	ZNF526 →	+4.807	+4.807	.008	.008	1	3
BLOOD_Leukemia	WDR24 →	+2.975	+3.794	.006	.006	1	3
BLOOD_Leukemia	KBTBD11 →	+5.560	+4.736	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 920 associations by consensus.

DOCK9 by TUBG2 expression — BREAST

Explore this box plot interactively →