TUBA1C

Across TCGA patient cohorts, TUBA1C mutation is significantly associated with the RNA expression of many other genes, with 311 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBA1C-associated genes across cancer lineages are LINC01180, TRBV5-2, and MTND4LP31. Each is linked with TUBA1C in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBA1C-to-partner and partner-to-TUBA1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01180 grouped by TUBA1C-low versus TUBA1C-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA1C→partner) and Y-score (partner→TUBA1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	LINC01180 →	+0.042	+4.361	.001	.006	3	2
SKCM	TRBV5-2 →	+0.186	+4.224	<.001	.002	3	2
BRCA	MTND4LP31 →	+0.118	+6.133	<.001	.001	3	2
UCEC	RNU6-222P →	+0.743	+3.487	<.001	<.001	3	2
UCEC	HPRT1P3 →	+0.116	+2.754	.001	.007	3	2
BLCA	RN7SL98P →	+0.118	+5.329	.008	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 311 associations by consensus.

LINC01180 by TUBA1C expression — READ

Explore this box plot interactively →