Q-omics provides the consensus-scored TRBV5-2 profile across patient tissues and cancer cell-line models. TRBV5-2 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, TRBV5-2 RNA expression shows 8,630 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, and THYM as cancer lineages where TRBV5-2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes TRBV5-2 survival associations across molecular data types. TRBV5-2 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

TRBV5-2 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	13	KIRC (144)	view →

This table ranks reproducible TRBV5-2 RNA expression–survival associations across cancer types. High TRBV5-2 expression shows unfavorable associations in KIRC, COAD, LIHC, UCEC and TGCT, but favorable associations in PAAD. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for TRBV5-2 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	II,III,IV	0.496	0.806	<.001	144	view →
COAD	DFS	Tertile	III,IV	0.258	0.675	.001	96	view →
LIHC	DFS	Tertile	All	0.078	0.559	<.001	63	view →
UCEC	DFS	Tertile	All	0.346	0.662	<.001	48	view →
TGCT	DFS	Tertile	II,III,IV	0.015	0.919	<.001	36	view →
PAAD	DFS	Tertile	II,III,IV	1.000	0.259	.009	18	view →

Pink = unfavorable, green = favorable. all 13 lineages →

TRBV5-2-KIRC (OS)

Kaplan–Meier survival curve for TRBV5-2 RNA expression in KIRC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with TRBV5-2 in patient tissues and cancer cell lines. In patient samples, TRBV5-2 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	8,630	THYM (2121)	view →
Function (RNA)	6,607	STAD (5846)	view →