TUBA1C

Across TCGA pan-cancer cohorts, TUBA1C RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of TUBA1C’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TUBA1C RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TUBA1C is over-expressed in tumor.

KIRC, KIRP, and HNSC are the cancer types where TUBA1C tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TUBA1C RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.993	<.001	12	view →
KIRP	Male	III,IV	+1.285	<.001	11	view →
HNSC	Male	All	+1.358	<.001	10	view →
BLCA	All	III,IV	+1.291	<.001	10	view →
COAD	Female	All	+0.671	<.001	10	view →
LUSC	All	III,IV	+2.229	<.001	9	view →
LUAD	All	III,IV	+1.155	<.001	9	view →
LIHC	Male	II,III,IV	+1.359	<.001	8	view →
UCEC	All	III,IV	+1.917	<.001	6	view →
BRCA	All	III,IV	+1.453	<.001	6	view →
STAD	All	All	+1.051	.001	6	view →
CHOL	Male	All	+3.058	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

TUBA1C–KIRC

Open the KIRC breakdown →