TUBA1C

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TUBA1C mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TUBA1C-associated genes across cancer lineages are TBC1D3. Each is linked with TUBA1C in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBA1C-to-partner and partner-to-TUBA1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D3 grouped by TUBA1C-low versus TUBA1C-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA1C→partner) and Y-score (partner→TUBA1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINETBC1D3 →+0.063+2.688<.001.00831
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

TBC1D3 by TUBA1C expression — LARGE_INTESTINE

Box plot of TBC1D3 in TUBA1C-low vs TUBA1C-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration