TUB

Across TCGA patient cohorts, TUB protein abundance is significantly associated with the RNA expression of many other genes, with 9,237 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TUB-associated genes across cancer lineages are NAP1L3, JAM2, and GHR. Each is linked with TUB in more than 4 cancer types. Because this analysis shows association rather than direction, both TUB-to-partner and partner-to-TUB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUB versus NAP1L3 in UCEC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUB→partner) and Y-score (partner→TUB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NAP1L3 →	+0.792	+0.319	<.001	.002	3	5
GBM	JAM2 →	+0.627	+0.383	<.001	<.001	3	5
HNSC	GHR →	+0.978	+1.164	<.001	<.001	3	4
GBM	ADGRB3 →	+1.317	+0.538	<.001	<.001	3	4
GBM	FXYD6 →	+1.233	+0.447	<.001	<.001	3	4
GBM	CNKSR2 →	+0.672	+0.287	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,237 associations by consensus.

TUB vs NAP1L3 — UCEC

Explore this scatter interactively →