Q-omics provides the consensus-scored TTC39A-AS1 profile across patient tissues and cancer cell-line models. TTC39A-AS1 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in BRCA. Among the 18 cancer types available for tumor–normal comparison, TTC39A-AS1 is differentially expressed in 11, with the highest sampling consensus in HNSC. Additionally, TTC39A-AS1 RNA expression shows 12,460 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight BRCA, HNSC, and ESCA as cancer lineages where TTC39A-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TTC39A-AS1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TTC39A-AS1 survival associations across molecular data types. TTC39A-AS1 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TTC39A-AS1 RNA expression–survival associations across cancer types. High TTC39A-AS1 expression shows unfavorable associations in KIRP, LGG and DLBC, but favorable associations in BRCA, HNSC and STAD. The BRCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify BRCA as the clearest survival context for TTC39A-AS1 RNA expression.
This table summarizes TTC39A-AS1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for TTC39A-AS1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TTC39A-AS1 shows lower tumor expression in HNSC, LUAD and LUSC and higher tumor expression in KIRP, LIHC and BRCA. The HNSC box plot shows higher TTC39A-AS1 RNA expression in normal versus tumor tissue (log2 FC = −0.628, t-test p < 0.001).
This table shows molecular features associated with TTC39A-AS1 in patient tissues and cancer cell lines. In patient samples, TTC39A-AS1 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.
