TTC39A-AS1

Across TCGA pan-cancer cohorts, TTC39A-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TTC39A-AS1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TTC39A-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TTC39A-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and HNSC show a favorable association.

BRCA, KIRP, and LGG are the cancer types where TTC39A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	II,III,IV	0.981	0.933	<.001	89	view →
KIRP	OS	Tertile	III,IV	0.262	0.809	.001	61	view →
LGG	DFS	Tertile	All	0.659	0.780	<.001	41	view →
HNSC	OS	Median	All	0.815	0.720	.011	35	view →
STAD	OS	Quartile	All	0.662	0.392	.009	27	view →
DLBC	DFS	Tertile	III,IV	0.070	0.855	.008	18	view →
PRAD	DFS	Tertile	All	0.955	0.899	.013	18	view →
LUAD	DFS	Median	IV	0.687	0.327	.005	13	view →
READ	DFS	Tertile	II,III,IV	0.843	0.348	.010	10	view →
ACC	OS	Quartile	All	1.000	0.848	.012	10	view →
GBM	DFS	Tertile	All	0.225	0.422	.018	9	view →
CHOL	DFS	Median	III,IV	0.133	0.779	.038	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TTC39A-AS1–BRCA (OS)

Open the BRCA breakdown →