TSNAX-DISC1

Across TCGA patient cohorts, TSNAX-DISC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,754 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TSNAX-DISC1-associated GO terms across cancer lineages are Cytoplasmic translational initiation, Regulation of chromatin organization, and Microtubule polymerization. Each is linked with TSNAX-DISC1 in more than 23 cancer types. Because this analysis shows association rather than direction, both TSNAX-DISC1-to-partner and partner-to-TSNAX-DISC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translational initiation grouped by TSNAX-DISC1-low versus TSNAX-DISC1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSNAX-DISC1→partner) and Y-score (partner→TSNAX-DISC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cytoplasmic translational initiation →	+0.048	+0.018	<.001	<.001	3	24
STAD	Regulation of chromatin organization →	+0.050	+0.023	<.001	<.001	3	23
STAD	Microtubule polymerization →	+0.045	+0.022	<.001	<.001	3	23
STAD	Macromolecule methylation →	+0.040	+0.019	<.001	<.001	3	23
STAD	Regulation of chromosome organization →	+0.045	+0.024	<.001	<.001	3	23
STAD	Organelle disassembly →	+0.047	+0.021	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,754 associations by consensus.

Cytoplasmic translational initiation by TSNAX-DISC1 expression — STAD

Explore this box plot interactively →