Q-omics provides the consensus-scored TSNAX-DISC1 profile across patient tissues and cancer cell-line models. TSNAX-DISC1 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, TSNAX-DISC1 is differentially expressed in 8, with the highest sampling consensus in KIRC. Additionally, TSNAX-DISC1 RNA expression shows 12,139 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight HNSC, KIRC, and THYM as cancer lineages where TSNAX-DISC1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TSNAX-DISC1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TSNAX-DISC1 survival associations across molecular data types. TSNAX-DISC1 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TSNAX-DISC1 RNA expression–survival associations across cancer types. High TSNAX-DISC1 expression shows unfavorable associations in COAD, KICH, UVM, STAD and ESCA, but favorable associations in HNSC. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for TSNAX-DISC1 RNA expression.
This table summarizes TSNAX-DISC1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for TSNAX-DISC1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TSNAX-DISC1 shows higher tumor expression in KIRC, KIRP, LUAD, BLCA, CHOL and LUSC. The KIRC box plot shows higher TSNAX-DISC1 RNA expression in tumor versus normal tissue (log2 FC = +0.015, t-test p < 0.001).
This table shows molecular features associated with TSNAX-DISC1 in patient tissues and cancer cell lines. In patient samples, TSNAX-DISC1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, TSNAX-DISC1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BREAST.
