Across TCGA patient cohorts, TSEN15 mutation is significantly associated with the RNA expression of many other genes, with 90 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSEN15-associated genes across cancer lineages are MIR6870, RNU6-1313P, and RNA5SP410. Each is linked with TSEN15 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSEN15-to-partner and partner-to-TSEN15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSEN15→partner) and Y-score (partner→TSEN15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6870 →	+0.597	+3.174	<.001	.002	3	2
COAD	RNU6-1313P →	+0.593	+7.741	<.001	.009	3	2
UCEC	RNA5SP410 →	+0.612	+2.789	.006	.004	3	2
UCEC	MIR7702 →	+0.373	+5.060	<.001	.001	3	1
UCEC	RN7SL736P →	+0.332	+2.806	.004	.003	3	1
COAD	RNU6-533P →	+0.571	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 90 associations by consensus.

Exploration

TSEN15 survival (RNA) · tumor vs normal (RNA) · all TSEN15 data types