Across TCGA patient cohorts, TSBP1 mutation is significantly associated with the RNA expression of many other genes, with 2,593 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSBP1-associated genes across cancer lineages are DPP3P2, RPLP1P13, and LINC01496. Each is linked with TSBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSBP1-to-partner and partner-to-TSBP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSBP1→partner) and Y-score (partner→TSBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DPP3P2 →	+0.205	+3.941	<.001	.002	3	2
COAD	RPLP1P13 →	+0.510	+3.730	<.001	.006	3	2
COAD	LINC01496 →	+0.121	+4.707	.002	<.001	3	2
COAD	ELOAP1 →	+0.022	+4.595	.001	.004	3	2
COAD	FAM204DP →	+0.186	+4.730	<.001	<.001	3	2
SKCM	LINC01275 →	+0.350	+2.305	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,593 associations by consensus.

Exploration

TSBP1 survival (RNA) · tumor vs normal (RNA) · all TSBP1 data types