TRPT1

Across TCGA patient cohorts, TRPT1 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRPT1-associated genes across cancer lineages are RNU6-1213P, MIR8071-1, and MIR26A1. Each is linked with TRPT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRPT1-to-partner and partner-to-TRPT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1213P grouped by TRPT1-low versus TRPT1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPT1→partner) and Y-score (partner→TRPT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-1213P →	+0.508	+7.930	<.001	.008	3	2
UCEC	MIR8071-1 →	+1.561	+3.799	<.001	.003	3	1
CESC	MIR26A1 →	+1.105	+5.306	<.001	.006	3	1
CESC	KRTAP20-4 →	+0.400	+7.164	<.001	<.001	3	1
CESC	SNORD96B →	+0.642	+5.539	<.001	.004	3	1
CESC	TXNL4AP1 →	+0.216	+5.539	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

RNU6-1213P by TRPT1 expression — LUAD

Explore this box plot interactively →