TRPT1

Across TCGA pan-cancer cohorts, TRPT1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of TRPT1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TRPT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRPT1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, BLCA, and LUSC are the cancer types where TRPT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRPT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	+0.475	<.001	11	view →
BLCA	Male	All	+0.755	<.001	10	view →
LUSC	Female	All	+0.717	<.001	9	view →
LUAD	Female	II,III,IV	+0.663	<.001	9	view →
LIHC	Female	II,III,IV	+1.230	<.001	8	view →
UCEC	All	All	+1.003	<.001	6	view →
BRCA	All	III,IV	+0.475	<.001	6	view →
COAD	All	All	+0.359	<.001	6	view →
CHOL	All	All	+0.991	<.001	3	view →
STAD	Male	II,III,IV	+0.285	.013	3	view →
ESCA	All	All	+0.372	.003	2	view →
PRAD	All	All	+0.173	.042	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

TRPT1–KIRC

Open the KIRC breakdown →