TRPT1

Across TCGA pan-cancer cohorts, TRPT1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated TRPT1 data layer compared with 1 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher TRPT1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRPT1 expression acts as an unfavorable survival marker, although some lineages such as MESO and CHOL show a favorable association.

KICH, ACC, and KIRC are the cancer types where TRPT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	III,IV	0.124	0.913	<.001	95	view →
ACC	DFS	Median	All	0.224	0.668	<.001	85	view →
KIRC	DFS	Quartile	All	0.780	0.918	.003	58	view →
MESO	OS	Tertile	All	0.459	0.258	.005	33	view →
CHOL	DFS	Tertile	II,III,IV	0.607	0.146	.006	32	view →
BLCA	OS	Median	II,III,IV	0.688	0.544	.002	28	view →
OV	OS	Median	IV	0.722	0.504	.013	26	view →
LGG	DFS	Median	All	0.771	0.876	.002	22	view →
LIHC	OS	Median	II,III,IV	0.566	0.814	.001	19	view →
READ	OS	Tertile	IV	0.379	0.910	.003	15	view →
KIRP	OS	Quartile	All	0.774	0.486	.016	15	view →
CESC	OS	Quartile	II,III,IV	0.601	0.850	.038	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

TRPT1–KICH (DFS)

Open the KICH breakdown →