Q-omics provides the consensus-scored KRTAP20-4 profile across patient tissues and cancer cell-line models. KRTAP20-4 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, KRTAP20-4 is differentially expressed in 2, with the highest sampling consensus in PRAD. Additionally, KRTAP20-4 RNA expression shows 9,186 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight COAD, PRAD, and TGCT as cancer lineages where KRTAP20-4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for KRTAP20-4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes KRTAP20-4 survival associations across molecular data types. KRTAP20-4 RNA expression shows survival associations in the most cancer types (14), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible KRTAP20-4 RNA expression–survival associations across cancer types. High KRTAP20-4 expression shows unfavorable associations in COAD, STAD, KIRP, HNSC, UCS and THYM. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for KRTAP20-4 RNA expression.
This table summarizes KRTAP20-4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in PRAD for RNA.
This table ranks reproducible tumor–normal expression differences for KRTAP20-4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. KRTAP20-4 shows higher tumor expression in PRAD and LIHC. The PRAD box plot shows higher KRTAP20-4 RNA expression in tumor versus normal tissue (log2 FC = +0.522, t-test p = .005).
This table shows molecular features associated with KRTAP20-4 in patient tissues and cancer cell lines. In patient samples, KRTAP20-4 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
