TRPC4AP

Across TCGA patient cohorts, TRPC4AP mutation is significantly associated with the RNA expression of many other genes, with 3,597 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRPC4AP-associated genes across cancer lineages are KRTAP13-5P, TTTY18, and MIR6736. Each is linked with TRPC4AP in more than 3 cancer types. Because this analysis shows association rather than direction, both TRPC4AP-to-partner and partner-to-TRPC4AP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP13-5P grouped by TRPC4AP-low versus TRPC4AP-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPC4AP→partner) and Y-score (partner→TRPC4AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	KRTAP13-5P →	+0.581	+4.798	<.001	.006	3	4
HNSC	TTTY18 →	+0.619	+5.015	<.001	.009	3	3
SKCM	MIR6736 →	+0.639	+4.440	<.001	.006	3	2
UCEC	TTC9C →	+0.302	+1.794	<.001	<.001	3	2
UCEC	PATL1 →	+0.385	+1.850	.001	.001	3	2
UCEC	TMEM126A →	+0.473	+2.000	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,597 associations by consensus.

KRTAP13-5P by TRPC4AP expression — STAD

Explore this box plot interactively →