TRMT11

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRMT11 mutation is significantly associated with the RNA expression of many other genes, with 1,761 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRMT11-associated genes across cancer lineages are RN7SL248P, RNA5SP325, and MIR5704. Each is linked with TRMT11 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRMT11-to-partner and partner-to-TRMT11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by TRMT11-low versus TRMT11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT11→partner) and Y-score (partner→TRMT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL248P →+0.051+2.915<.001.00733
BLCARNA5SP325 →+0.196+4.433<.001.00732
BRCAMIR5704 →+0.446+8.055<.001.00732
LUADEXOGP1 →+0.048+5.315<.001.00332
LUADB3GNTL1P2 →+0.230+5.198<.001.00132
SKCMKRTAP27-1 →+0.052+5.199<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,761 associations by consensus.

RN7SL248P by TRMT11 expression — UCEC

Box plot of RN7SL248P in TRMT11-low vs TRMT11-high samples in UCEC.

Explore this box plot interactively →

Exploration