TPRX1

Across TCGA patient cohorts, TPRX1 protein abundance is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TPRX1-associated genes across cancer lineages are RERGL, SDCBP2, and IGLL1. Each is linked with TPRX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPRX1-to-partner and partner-to-TPRX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPRX1 versus RERGL in PDAC, with a Pearson correlation of -0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPRX1→partner) and Y-score (partner→TPRX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RERGL →	-1.206	-0.829	<.001	<.001	3	1
PDAC	SDCBP2 →	-1.251	-0.945	.001	.002	3	1
PDAC	IGLL1 →	-0.167	-0.676	.001	.009	3	1
PDAC	SLC10A6 →	-0.825	-0.674	.003	.006	3	1
PDAC	SCUBE3 →	+0.993	+0.679	.002	.006	3	1
PDAC	LINC01620 →	-0.180	-0.875	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

TPRX1 vs RERGL — PDAC

Explore this scatter interactively →