TOMM70

Across TCGA patient cohorts, TOMM70 mutation is significantly associated with the RNA expression of many other genes, with 1,929 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TOMM70-associated genes across cancer lineages are RNA5SP412, RNU1-46P, and TRAJ10. Each is linked with TOMM70 in more than 1 cancer types. Because this analysis shows association rather than direction, both TOMM70-to-partner and partner-to-TOMM70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by TOMM70-low versus TOMM70-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOMM70→partner) and Y-score (partner→TOMM70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.597	+2.137	<.001	<.001	3	2
UCEC	RNU1-46P →	+0.120	+3.175	<.001	.004	3	2
UCEC	TRAJ10 →	+0.454	+1.769	.001	.003	3	2
UCEC	MIR6803 →	+0.109	+3.954	<.001	.006	3	2
COAD	RNU6-33P →	+1.084	+3.838	<.001	.005	3	2
UCEC	TOMM22P5 →	+0.189	+1.784	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,929 associations by consensus.

RNA5SP412 by TOMM70 expression — UCEC

Explore this box plot interactively →