TOMM70

Across TCGA pan-cancer cohorts, TOMM70 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of TOMM70’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TOMM70 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TOMM70 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

KIRC, THCA, and LUAD are the cancer types where TOMM70 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TOMM70 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.770	<.001	11	view →
THCA	Male	III,IV	−0.514	<.001	10	view →
LUAD	Male	III,IV	+0.868	<.001	9	view →
LIHC	Male	All	+0.831	<.001	9	view →
LUSC	Male	II,III,IV	+1.191	<.001	8	view →
KIRP	All	All	+0.611	<.001	8	view →
HNSC	All	All	+0.344	<.001	8	view →
COAD	Male	All	+0.428	<.001	6	view →
BRCA	All	III,IV	+0.410	<.001	6	view →
STAD	All	II,III,IV	+0.548	.004	5	view →
CHOL	All	All	+0.668	<.001	4	view →
KICH	All	All	−0.667	.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

TOMM70–KIRC

Open the KIRC breakdown →