TOMM70

Across TCGA pan-cancer cohorts, TOMM70 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated TOMM70 data layer compared with 2 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher TOMM70 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TOMM70 expression acts as an unfavorable survival marker, although some lineages such as KIRC and READ show a favorable association.

ACC, KIRC, and LIHC are the cancer types where TOMM70 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.251	0.627	<.001	80	view →
KIRC	DFS	Tertile	All	0.720	0.528	<.001	62	view →
LIHC	OS	Tertile	All	0.704	0.856	<.001	49	view →
KICH	OS	Tertile	II,III,IV	0.605	1.000	.005	47	view →
PAAD	OS	Tertile	All	0.352	0.607	.004	39	view →
UCEC	DFS	Median	All	0.794	0.877	.003	38	view →
READ	OS	Median	All	0.886	0.323	.005	34	view →
LGG	DFS	Median	All	0.471	0.282	.002	13	view →
GBM	DFS	Tertile	All	0.444	0.172	.001	12	view →
BLCA	OS	Median	III,IV	0.675	0.480	.023	12	view →
SARC	DFS	Tertile	All	0.301	0.544	.007	12	view →
LUAD	DFS	Tertile	IV	1.000	0.243	.011	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

TOMM70–ACC (DFS)

Open the ACC breakdown →