TOMM70

Across TCGA cell cohorts, TOMM70 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,984 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TOMM70-associated GO terms across cancer lineages are Protein insertion into mitochondrial outer membrane, tRNA wobble cytosine modification, and Outer mitochondrial membrane organization. Each is linked with TOMM70 in more than 16 cancer types. Because this analysis shows association rather than direction, both TOMM70-to-partner and partner-to-TOMM70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein insertion into mitochondrial outer membrane grouped by TOMM70-low versus TOMM70-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TOMM70→partner) and Y-score (partner→TOMM70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein insertion into mitochondrial outer membrane →	+0.095	+0.735	<.001	<.001	3	17
LIVER	tRNA wobble cytosine modification →	+0.090	+0.838	.001	.001	3	13
BONE	Outer mitochondrial membrane organization →	+0.120	+0.732	.002	.003	2	12
OVARY	rRNA 5'-end processing →	+0.110	+0.465	<.001	.006	3	11
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome →	+0.115	+0.863	.001	.002	3	11
OVARY	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.110	+0.465	<.001	.006	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,984 associations by consensus.

Protein insertion into mitochondrial outer membrane by TOMM70 expression — UPPER_AERODIGESTIVE_TRACT

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