TOMM70

Across TCGA cell cohorts, TOMM70 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TOMM70-associated genes across cancer lineages are MMP26 and ETDC. Each is linked with TOMM70 in more than 1 cancer types. Because this analysis shows association rather than direction, both TOMM70-to-partner and partner-to-TOMM70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by TOMM70-low versus TOMM70-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOMM70→partner) and Y-score (partner→TOMM70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MMP26 →	+0.039	+3.632	<.001	.003	3	1
LUNG_NSCLC_LUAD	ETDC →	+0.523	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MMP26 by TOMM70 expression — LARGE_INTESTINE

Explore this box plot interactively →