Across TCGA patient cohorts, TOMM20L mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TOMM20L-associated genes across cancer lineages are RNU6-1069P, LINC00905, and MIR588. Each is linked with TOMM20L in more than 1 cancer types. Because this analysis shows association rather than direction, both TOMM20L-to-partner and partner-to-TOMM20L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOMM20L→partner) and Y-score (partner→TOMM20L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1069P →	+1.778	+3.815	<.001	.009	3	1
LUAD	LINC00905 →	+0.018	+5.217	.001	.007	3	1
LUAD	MIR588 →	+0.721	+5.631	<.001	.004	3	1
LUAD	OR52B4 →	+0.047	+5.888	<.001	.002	3	1
LUAD	CDRT15P2 →	+0.120	+5.798	<.001	.003	3	1
LUAD	MRPS18BP2 →	+0.065	+5.554	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

TOMM20L survival (RNA) · tumor vs normal (RNA) · all TOMM20L data types