TNIP1

Across TCGA patient cohorts, TNIP1 mutation is significantly associated with the RNA expression of many other genes, with 2,882 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNIP1-associated genes across cancer lineages are MIR549A, RNU1-6P, and SCP2D1. Each is linked with TNIP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TNIP1-to-partner and partner-to-TNIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR549A grouped by TNIP1-low versus TNIP1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNIP1→partner) and Y-score (partner→TNIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR549A →	+0.221	+4.147	<.001	.009	3	3
COAD	RNU1-6P →	+0.254	+5.557	<.001	.001	3	2
SKCM	SCP2D1 →	+0.035	+5.163	<.001	.002	3	2
STAD	RNU6-800P →	+0.643	+3.580	<.001	.009	3	2
HNSC	PRKG2-AS1 →	+0.189	+4.428	<.001	.002	3	2
SKCM	SNORD116-10 →	+0.216	+4.302	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,882 associations by consensus.

MIR549A by TNIP1 expression — BLCA

Explore this box plot interactively →