Q-omics provides the consensus-scored RNU1-6P profile across patient tissues and cancer cell-line models. RNU1-6P expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in HNSC. Additionally, RNU1-6P RNA expression shows 4,911 significant gene co-expression associations, with the highest sampling consensus in STAD. Together, these results highlight HNSC, and STAD as cancer lineages where RNU1-6P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU1-6P survival associations across molecular data types. RNU1-6P RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU1-6P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	11	HNSC (63)	view →

This table ranks reproducible RNU1-6P RNA expression–survival associations across cancer types. High RNU1-6P expression shows unfavorable associations in HNSC, THYM, BRCA, COAD and LGG, but favorable associations in ESCA. The HNSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for RNU1-6P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.195	0.618	<.001	63	view →
THYM	DFS	Tertile	All	0.117	0.892	<.001	54	view →
BRCA	DFS	Tertile	IV	0.175	0.730	.005	36	view →
COAD	DFS	Tertile	III,IV	0.140	0.671	<.001	36	view →
LGG	OS	Tertile	All	0.405	0.803	<.001	27	view →
ESCA	OS	Tertile	III,IV	1.000	0.372	.032	18	view →

Pink = unfavorable, green = favorable. all 11 lineages →

RNU1-6P-HNSC (OS)

Kaplan–Meier survival curve for RNU1-6P RNA expression in HNSC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU1-6P in patient tissues and cancer cell lines. In patient samples, RNU1-6P shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	4,911	STAD (1395)	view →
Function (RNA)	3,136	STAD (2298)	view →