TMSB15B

Across TCGA cell cohorts, TMSB15B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,604 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMSB15B-associated GO terms across cancer lineages are Regulation of mitotic metaphase/anaphase transition, Negative regulation of mitotic metaphase/anaphase transition, and Chromosome localization. Each is linked with TMSB15B in more than 11 cancer types. Because this analysis shows association rather than direction, both TMSB15B-to-partner and partner-to-TMSB15B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic metaphase/anaphase transition grouped by TMSB15B-low versus TMSB15B-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMSB15B→partner) and Y-score (partner→TMSB15B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of mitotic metaphase/anaphase transition →	+0.114	+2.076	<.001	<.001	3	12
STOMACH	Negative regulation of mitotic metaphase/anaphase transition →	+0.144	+1.806	<.001	<.001	3	12
SOFT_TISSUE	Chromosome localization →	+0.097	+2.480	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of mitotic sister chromatid segregation →	+0.123	+2.192	.004	.002	3	12
LUNG_NSCLC_LUSC	Regulation of chromosome segregation →	+0.123	+2.647	.003	<.001	3	12
LUNG_NSCLC_LUSC	Chromosome segregation →	+0.102	+2.372	.004	.008	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,604 associations by consensus.

Regulation of mitotic metaphase/anaphase transition by TMSB15B expression — BLOOD_Lymphoma

Explore this box plot interactively →