TMPRSS11E

Across TCGA cell cohorts, TMPRSS11E protein abundance is significantly associated with the RNA expression of many other genes, with 2,702 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMPRSS11E-associated genes across cancer lineages are GOT2, PSME3IP1, and CYP39A1. Each is linked with TMPRSS11E in more than 9 cancer types. Because this analysis shows association rather than direction, both TMPRSS11E-to-partner and partner-to-TMPRSS11E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMPRSS11E versus GOT2 in BLOOD_Myeloma, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS11E→partner) and Y-score (partner→TMPRSS11E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	GOT2 →	+1.577	+1.134	.002	.009	3	10
LUNG_NSCLC_LUAD	PSME3IP1 →	+0.792	+0.708	<.001	<.001	3	8
BLOOD_Lymphoma	CYP39A1 →	+1.759	+0.729	.002	<.001	3	6
LUNG_NSCLC_LUAD	LONP2 →	+0.648	+0.616	.002	<.001	3	6
BLOOD_Myeloma	CIAPIN1 →	+0.967	+0.769	.007	.001	2	7
BLOOD_Myeloma	CSNK2A2 →	+1.035	+0.916	.006	.003	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,702 associations by consensus.

TMPRSS11E vs GOT2 — BLOOD_Myeloma

Explore this scatter interactively →