Q-omics provides the consensus-scored CIAPIN1 profile across patient tissues and cancer cell-line models. CIAPIN1 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, CIAPIN1 is differentially expressed in 15, with the highest sampling consensus in COAD. Additionally, CIAPIN1 protein abundance shows 21,463 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight HNSC, COAD, and LSCC as cancer lineages where CIAPIN1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CIAPIN1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CIAPIN1 survival associations across molecular data types. CIAPIN1 RNA expression shows survival associations in the most cancer types (25), followed by mutation status (6) and mass-spec protein abundance (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CIAPIN1 RNA expression–survival associations across cancer types. High CIAPIN1 expression shows unfavorable associations in HNSC, ACC, LIHC, BLCA and SKCM, but favorable associations in SCLC. The HNSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for CIAPIN1 RNA expression.
This table summarizes CIAPIN1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 15, while mass-spec protein shows differences in 5. The strongest signals are observed in HNSC for RNA and HNSC for protein.
This table ranks reproducible tumor–normal expression differences for CIAPIN1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CIAPIN1 shows lower tumor expression in KICH and higher tumor expression in COAD, HNSC, KIRP, BLCA and LIHC. The COAD box plot shows higher CIAPIN1 RNA expression in tumor versus normal tissue (log2 FC = +0.925, t-test p < 0.001).
This table shows molecular features associated with CIAPIN1 in patient tissues and cancer cell lines. In patient samples, CIAPIN1 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set. In cancer cell lines, CIAPIN1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BONE, while CRISPR and shRNA rows add functional-dependency signals in BLOOD_Leukemia and SKIN.
