CIAPIN1

Across TCGA pan-cancer cohorts, CIAPIN1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CIAPIN1 data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CIAPIN1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CIAPIN1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and UCEC show a favorable association.

PDAC, UCEC, and LSCC are the cancer types where CIAPIN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	III,IV	0.535	0.177	.010	14	view →
UCEC	OS	Tertile	III,IV	1.000	0.281	.022	8	view →
LSCC	OS	Median	All	0.826	0.943	.007	3	view →
LUAD	OS	Median	All	0.594	0.855	.029	2	view →
CCRCC	OS	Median	II,III,IV	0.442	0.838	.045	1	view →
HNSC	DFS	Median	All	0.704	0.558	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CIAPIN1–PDAC (DFS)

Open the PDAC breakdown →