Across TCGA patient cohorts, TMEM88B RNA expression is significantly associated with the protein abundance of many other proteins, with 10,266 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM88B-associated proteins across cancer lineages are NUCB2, CLINT1, and TCF25. Each is linked with TMEM88B in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM88B-to-partner and partner-to-TMEM88B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM88B→partner) and Y-score (partner→TMEM88B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NUCB2 →	-0.444	-0.676	<.001	<.001	3	4
COAD	CLINT1 →	-0.210	-0.139	<.001	<.001	3	3
CCRCC	TCF25 →	-0.220	-0.084	<.001	.001	3	3
GBM	TUBB4A →	+0.903	+1.251	<.001	<.001	3	3
CCRCC	PRKG1 →	+0.437	+0.130	.002	.002	3	3
CCRCC	MPRIP →	+0.290	+0.088	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,266 associations by consensus.

Exploration

TMEM88B survival (RNA) · tumor vs normal (RNA) · all TMEM88B data types