TMEM59L

Across TCGA patient cohorts, TMEM59L RNA expression is significantly associated with the protein abundance of many other proteins, with 14,368 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM59L-associated proteins across cancer lineages are KANK2, PALM2AKAP2, and PCOLCE. Each is linked with TMEM59L in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM59L-to-partner and partner-to-TMEM59L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM59L versus KANK2 in COAD, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM59L→partner) and Y-score (partner→TMEM59L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	KANK2 →	+0.700	+0.407	<.001	<.001	3	7
CCRCC	PALM2AKAP2 →	+0.482	+0.232	<.001	<.001	3	6
CCRCC	PCOLCE →	+0.725	+0.193	<.001	<.001	3	6
COAD	SORBS1 →	+0.949	+0.377	<.001	<.001	3	6
COAD	COL18A1 →	+0.486	+0.397	<.001	<.001	3	6
BRCA	AKAP12_T21 →	+1.246	+0.893	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,368 associations by consensus.

TMEM59L vs KANK2 — COAD

Explore this scatter interactively →