TMEM35B

Across TCGA patient cohorts, TMEM35B protein abundance is significantly associated with the RNA expression of many other genes, with 1,847 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM35B-associated genes across cancer lineages are WDR20, RNU7-11P, and RIMS3. Each is linked with TMEM35B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM35B-to-partner and partner-to-TMEM35B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM35B versus WDR20 in LUAD, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM35B→partner) and Y-score (partner→TMEM35B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	WDR20 →	+0.374	+0.704	.001	.002	3	2
UCEC	RNU7-11P →	+2.455	+0.594	<.001	.001	3	2
LUAD	RIMS3 →	+0.953	+0.646	.008	.006	3	2
LUAD	SOX2 →	-1.793	-0.528	<.001	.003	3	2
CCRCC	P2RY8 →	-1.035	-0.356	<.001	.002	3	2
GBM	TMEM18 →	-0.469	-0.965	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,847 associations by consensus.

TMEM35B vs WDR20 — LUAD

Explore this scatter interactively →